Carotid artery intimal-medial thickness and left ventricular hypertrophy in children with elevated blood pressure.

摘要: Objectives. To determine the association between carotid artery intimal-medial thickness (cIMT) and left ventricular mass index (LVMI) in children with elevated blood pressure. Methods. Study subjects (n = 32; mean age: 13.9 ± 2.7 years) were untreated new referrals to a pediatric hypertension clinic confirmed LVM was calculated from 2-dimensionally guided m-mode echocardiographic measurements of ventricle. LVMI as (g)/height (m)2.7, hypertrophy (LVH) defined >95th percentile. Carotid duplex ultrasound performed by protocol experienced vascular sonographers who unaware echocardiography results. The thickest IMT complex far wall distal common measured longitudinal B-mode section using high-resolution linear array 8 MHz. Results. prevalence LVH increased cIMT 41% 28%, respectively. Subjects had higher (46.8 g/m2.7 vs 31.4 g/m2.7) than those normal cIMT. 89% (8 9) among compared 22% (5 23) positively correlated body (r 0.43), interventricular septal 0.58), posterior 0.54), 0.54). associated after accounting for age, gender, index. Conclusions. These findings raise possibility that ultrasound, indicating presence early arterial changes, may be useful predicting other cardiovascular sequelae hypertensive children.