Metabolites in contact with the rat digestive tract after ingestion of a phenolic-rich dietary fiber matrix.
作者： Sonia Touriño , Jara Pérez-Jiménez , María Luisa Mateos-Martín , Elisabet Fuguet , María Pilar Vinardell
DOI: 10.1021/JF200159F
关键词:
摘要: Grape antioxidant dietary fiber (GADF) is a phenolic-rich matrix. The aim of this work was to determine which phenolic compounds come into contact with colonic epithelial tissue after the ingestion GADF. By use HPLC-ESI-MS/MS techniques metabolites were detected in feces, cecal content, and from rats. Free (epi)catechin (EC) all three sources, more than 20 conjugated EC also feces. Fourteen microbially derived identified and/or tissue. These results show that during transit along digestive tract, proanthocyanidin oligomers polymers are depolymerized units. After GADF, free its conjugates, as well metabolites, intestine epithelium for 24 h may be partly responsible positive influence GADF on gut health.
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