The Aging of the Choroid

作者: Angelica Cerulli , Federico Regine , Giuseppe Carella

DOI: 10.1007/978-1-59745-507-7_11

关键词:

摘要: The first section of this chapter describes the anatomy and physiology choroid vascular pattern choroidal vessels. is fundamental importance for nourishment retina so that all alterations lead to a disfunction retinal pigment epithelium (RPE), Bruch's membrane, choriocapillary complex. various methods used study its pathologies in post-mortem studies vivo are described—injection chromopolimer, Indocyanine Green Angiografy, Doppler flow studies. Age-related changes analyzed. Alterations have been described layers choroid, which part physiologic aging process. In certain cases, they can cause disease, but sometimes border between pathologic age-related very hard identify. represents preferential target diseases. particular, we describe physiopathology such as hypertension, diabetes, AMD, atherosclerosis—so common elderly. diabetes AMD represent main causes blindness industrialized countries.

参考文章(79)
R P Burns, L Feeney-Burns, Clinico-morphologic correlations of drusen of Bruch's membrane. Transactions of the American Ophthalmological Society. ,vol. 78, pp. 206- 225 ,(1980)
R.S. Ramrattan, W.C. de Bruijn, T.L. van der Schaft, C.M. Mooy, P.G.H. Mulder, P.T.V.M. de Jong, Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging. Investigative Ophthalmology & Visual Science. ,vol. 35, pp. 2857- 2864 ,(1994)
Sohan Singh Hayreh, Macular lesions secondary to choroidal vascular disorders. International Ophthalmology. ,vol. 6, pp. 161- 170 ,(1983) , 10.1007/BF00127645
G A Lutty, D S McLeod, High-Resolution Histologic Analysis of the Human Choroidal Vasculature Investigative Ophthalmology & Visual Science. ,vol. 35, pp. 3799- 3811 ,(1994)
Robert Haimovici, Thomas F. Freddo, Donald L. Gantz, Donald M. Small, Shimon Rumelt, The lipid composition of drusen, Bruch's membrane, and sclera by hot stage polarizing light microscopy. Investigative Ophthalmology & Visual Science. ,vol. 42, pp. 1592- 1599 ,(2001)
Hayreh Ss, Acute choroidal ischaemia. Transactions of the ophthalmological societies of the United Kingdom. ,vol. 100, pp. 400- ,(1980)
W. Richard Green, Cheryl Enger, Age-related Macular Degeneration Histopathologic Studies Ophthalmology. ,vol. 100, pp. 1519- 1535 ,(1993) , 10.1016/S0161-6420(93)31466-1
K. U. Loffler, W. R. Lee, Basal linear deposit in the human macula. Graefes Archive for Clinical and Experimental Ophthalmology. ,vol. 224, pp. 493- 501 ,(1986) , 10.1007/BF02154735
Walter H. Stern, J. Terry Ernest, Microsphere Occlusion of the Choriocapillaris in Rhesus Monkeys American Journal of Ophthalmology. ,vol. 78, pp. 438- 448 ,(1974) , 10.1016/0002-9394(74)90231-1