摘要: VEGF is best known for its angiogenic properties. Not only does it promote the growth of new blood vessels during embryonic development, also important in adult, where plays a role maintaining an adequate supply oxygen and nutrients to most tissues. gene regulation controlled by different signalling pathways depending on context which expressed. Best understood induction expression hypoxia neonates adults, represents adaptive response metabolic stress. In contrast, mechanisms that control development are currently less clear.
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