Immunodeficiency in the chicken. II. Production of monomeric IgM following testosterone treatment or infection with Gumboro disease.
作者： J Ivanyi
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摘要: Chickens were treated at an early embryonal age with testosterone propionate or infected neonatally the virus producing Gumboro disease. Their sera subsequently fractionated by Sephadex G-200 chromatography, and showed a complete deficiency of IgG presence IgM which was eluted 7S protein fraction. Purified 125-I-labelled monomeric examined SDS-acrylamide gel electrophoresis found to contain both mu light chains, together chain intermediary size, absent from patterns 19S IgG.
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