Basis of bone strength vs. bone fragility: a review of determinants of age-related hip fracture risk.
作者： Danijela Djonic , Petar Milovanovic , Marija Djuric
DOI: 10.2298/SARH1308548D
关键词:
摘要: The burden of hip fractures in elderly population has been growing worldwide. A particular focus directed towards identifying persons at high risk fracture. However, bone mineral density (BMD), which is currently used in clinical settings as an indicator risk age-related fracture, cannot explain all fracture cases the elderly. In fact, fractures associated with numerous features that degrade bone strength. This review focuses on complexity could account for increased fragility advanced age. Besides a decrease BMD, various macroscopic and microscopic structural parameters, well as material composed, are subject to age-related changes. Therefore, order have more thorough assessment the risk, it essential provide integrative approaches combine BMD measure other relevant features. [Projekat Ministarstva nauke Republike Srbije, br. 45005]
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