Biological options to enhance periprosthetic bone mass
作者： E. Tsiridis , Z. Gamie , P.G. Conaghan , P.V. Giannoudis
DOI: 10.1016/J.INJURY.2007.02.051
关键词: Teriparatide 、 Bisphosphonate 、 Bioinformatics 、 Osteopenia 、 Osteoporosis 、 Antibacterial agent 、 Periprosthetic 、 Strontium ranelate 、 Implant failure 、 Medicine 、 Surgery
摘要: There is a potential for the use of pharmacological agents to enhance quality bone around total hip or knee prosthesis, reducing risk implant failure periprosthetic fracture. Bisphosphonates are currently used management postmenopausal osteoporosis and recent investigations also suggest role postoperative loss. Current evidence suggests that short-term gains may not be sustained in long term. Teriparatide parathyroid hormone 1-84 have been licensed treat investigated mass. In addition, other such as calcitonin strontium ranelate, non-anabolic doxycycline, recombinant OPG adeno-associated virus (rAAV) gene therapy, future provide solutions enhancing
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