Triggering of transient LES relaxations in ferrets: role of sympathetic pathways and effects of baclofen.

作者: Esther Staunton , Scott D. Smid , John Dent , L. Ashley Blackshaw

DOI: 10.1152/AJPGI.2000.279.1.G157

关键词:

摘要: Activation of gastric vagal mechanoreceptors by distention is thought to be the trigger for transient lower esophageal sphincter relaxations (TLESR), which lead gastroesophageal reflux. The cont...

参考文章(20)
Christopher J. Martin, John Patrikios, John Dent, Abolition of gas reflux and transient lower esophageal sphincter relaxation by vagal blockade in the dog. Gastroenterology. ,vol. 91, pp. 890- 896 ,(1986) , 10.1016/0016-5085(86)90691-8
F. Cervero, Sensory innervation of the viscera: peripheral basis of visceral pain Physiological Reviews. ,vol. 74, pp. 95- 138 ,(1994) , 10.1152/PHYSREV.1994.74.1.95
Amanda J. Page, L. Ashley Blackshaw, GABABReceptors Inhibit Mechanosensitivity of Primary Afferent Endings The Journal of Neuroscience. ,vol. 19, pp. 8597- 8602 ,(1999) , 10.1523/JNEUROSCI.19-19-08597.1999
R.D. Brtva, G.A. Iwamoto, J.C. Longhurst, Distribution of cell bodies for primary afferent fibers from the stomach of the cat. Neuroscience Letters. ,vol. 105, pp. 287- 293 ,(1989) , 10.1016/0304-3940(89)90635-6
E.R Partosoedarso, L.A Blackshaw, Vagal efferent fibre responses to gastric and oesophageal mechanical and chemical stimuli in the ferret. Journal of The Autonomic Nervous System. ,vol. 66, pp. 169- 178 ,(1997) , 10.1016/S0165-1838(97)00081-7
SMID, PAGE, O'DONNELL, LANGMAN, ROWLAND, BLACKSHAW, Oesophagitis-induced changes in capsaicin-sensitive tachykininergic pathways in the ferret lower oesophageal sphincter. Neurogastroenterology and Motility. ,vol. 10, pp. 403- 411 ,(1998) , 10.1046/J.1365-2982.1998.00118.X
John Dent, Gastro-Oesophageal Reflux Disease Digestion. ,vol. 59, pp. 433- 445 ,(1998) , 10.1159/000007521
Ravinder K. Mittal, Richard H. Holloway, Roberto Penagini, L. Ashley Blackshaw, John Dent, Transient lower esophageal sphincter relaxation Gastroenterology. ,vol. 109, pp. 601- 610 ,(1995) , 10.1016/0016-5085(95)90351-8