Factors affecting fecundity among sperm donors: a multivariate analysis.

摘要: Summary The study was aimed at identifying the predictors of male fertility potential among sperm donors. Fifty anonymous donors undergoing 683 intracervical insemination (ICI) cycles between January 2002 and December 2006 were retrospectively evaluated according to semen characteristics in terms reproduction rate (RR). We used RR as a parameter determine The overall 26.79%. There no significant differences low, mean high groups with regard most routine parameters. However, notably higher morphology ≥18% than <18% group (26.2% versus 19.4% respectively; P < 0.01). Both post-thaw total motility progressive proportional (P < 0.01). Differences seen when percentage propidium iodide-negative spermatozoa ≥45% 16.4% P < 0.01) DNA fragmentation index (DFI) <8% (37.5% 17.9% samples. Using stepwise linear regression analysis, normal morphology, motility, PI-negative spermatozoa, DFI had maximum power predict donor fecundity ICIs. Conclusion: integrity plasma membrane are crucial factors affecting Therefore, addition some these new tests analysis could significantly improve recruitment clinical pregnancy