Handbook of anxiety and fear

摘要: Section 1. Introduction to the Handbook on Fear and Anxiety Robert Blanchard, D. Caroline Guy Griebel David Nutt 2. Animal models of Anxiety, Defense Theoretical approaches modeling anxiety in animals Neil McNaughton Helio Zangrossi Jr., The use conditioning tasks model fear Michael S. Fanselow Ravikumar Ponnusamy Extinction fear: from animal studies clinical interventions Karyn M. Myers Davis Defensive behaviors, Blanchard Unconditioned Yoav Litvin, Nathan Pentkowski, Roger L. Pobbe, J. 3. Neural Systems for Fear, Brain mechanisms Pavlovian instrumental aversive Christopher K. Cain Joseph E. LeDoux systems activated response predators partial predator stimuli Newton Sabino Canteras A behavioral neural comparison unconditioned conditioned defensive behavior 4. Pharmacology Peptide receptor ligands treat disorders Thomas Steckler Subtype-selective GABAA/benzodiazepine treatment James Rowlett Modulation behaviors by 5-HT-interacting drugs Francisco Silveira Guimaraes, Antonio Padua Carobrez Frederico Guilherme Graeff glutamatergic system as a potential therapeutic target John F. Cryan Kumlesh Dev endocannabinoid responses Marco Bortolato Daniele Piomelli Genetic factors underlying anxiety-behaviour: meta-analysis rodent involving targeted mutations neurotransmission genes Catherine Belzung, Samuel Leman pharmacology anxiolysis Andrew Holmes 5. Anxiety: Clinical Experimental Considerations Phenomenology Nutt, Berta Garcia de Miguel Simon J.C. Davies How effective are current drug treatments disorders, how could they be improved? Baldwin Matthew Garner models: panic Gabriel Esquivel, Koen Schruers Eric Griez Principles findings human imaging Andrea Malizia Stress hormones Elizabeth A. Young, Abelson Israel Liberzon genetics Eduard Maron, Hettema Jakov Shlik