Nanodiamonds: Behavior in Biological Systems and Emerging Bioapplications
作者： Ivan Řehoř , Jitka Šlegerová , Jan Havlík , Helena Raabová , Jakub Hývl
DOI: 10.1007/978-3-319-22861-7_11
关键词:
摘要: In the past decade, nanodiamonds (NDs) have been recognized as a promising nanomaterial for bioapplications such bioimaging and drug delivery in nanoscale medicine. Here, we present comprehensive survey of current research on ND interactions with biological systems, including their biocompatibility, cellular internalization, localization, targeting by surface-attached ligands. We critically assess differences between different types NDs, detonation NDs high-pressure high-temperature (HPHT) NDs. describe NDs’ physicochemical properties, structure, available synthetic modifications small molecules biomolecules. Finally, discuss emerging medical applications these low-toxicity carbon nanoparticles.
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