Phytochemical screening, free radical scavenging and antimicrobial potential of Chromolaena odorata leaf extracts against pathogenic bacterium in wound infections– a multispectrum perspective

作者: Kavitha Vijayaraghavan , Johanna Rajkumar , Mohamed Ali Seyed

DOI: 10.1016/J.BCAB.2018.05.014

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摘要: Abstract The chronic bed ridden patients acquire infections are the main source of alarming morbidity and mortality as their correlation with fomites. Fomites reservoirs drug-resistant pathogens found in unhygienic clinical environment, which can infect leading to high nosocomial infection rates use antimicrobial drugs. search for drugs dietary supplements derived from plants have accelerated various therapeutic applications obtaining new agents natural resources is necessary develop alternative safe cost-effective health care. Hence, objective this research was perform a phytochemical analysis on Chromolaena odorata study antioxidant activities ethanolic aqueous extracts its leaves. In regard, phytochemicals obtained C.odorata investigated radical scavenging activity using 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) assay. revealed presence active ingredients such glycosides, steroids, saponins, phenols, flavonoids, terpenoids, tannins were categorized either primary metabolites, chlorophyll, proteins, amino acids, or secondary include terpenoids alkaloids. leaf extract showed higher antibacterial properties than exhibited. C. both ethanoloic subjected an agar diffusion method. Our results that could inhibit certain extent growth human like Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, cereus, Escherichia coli. summary, present highlights significance potentials, explain traditional plant animal medicine

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