Optimal management of nail disease in patients with psoriasis.

摘要: Psoriasis is a common skin disease, with nail involvement in approximately 80% of patients. Nail psoriasis often associated psoriatic arthropathy. Involvement the nails does not always have relationship type, gravity, extension, or duration psoriasis. can occur at any age and all parts surrounding structures be affected. Two clinical patterns manifestations been seen due to psoriasis: matrix bed involvement. In first case, irregular deep pitting, red spots lunula, crumbling, leukonychia are seen; second salmon patches, onycholysis erythematous border, subungual hyperkeratosis, splinter hemorrhages observed. These features more visible fingernails than toenails, where abnormalities diagnostic usually clinically indistinguishable from other conditions, especially onychomycosis. causes, above all, psychosocial aesthetic problems, but many patients complain about functional damage. Diagnosis histopathology necessary only selected cases. has an unpredictable course but, most cases, disease chronic complete remissions uncommon. Sun exposure improve may even worsen There no curative treatments. Treatment includes different types medications, topical therapy systemic therapy, according severity extension disease. Moreover, we should underestimate use biological agents new lasers iontophoresis. This review offers investigation treatment options for optimal management