Toll-like receptors stimulate human neutrophil function
作者： Andrew D. Luster , Fumitaka Hayashi , Terry K. Means
DOI: 10.1182/BLOOD-2003-04-1078
关键词:
摘要: The first immune cell to arrive at the site of infection is the neutrophil. Upon arrival, neutrophils quickly initiate microbicidal functions, including the production of antimicrobial products and proinflammatory cytokines that serve to contain infection. This allows the acquired immune system enough time to generate sterilizing immunity and memory. Neutrophils detect the presence of a pathogen through germ line-encoded receptors that recognize microbe-associated molecular patterns. In vertebrates, the best characterized of …
ashpublications.org
bloodjournal.org参考文章(47)
Mark B. Hampton, Anthony J. Kettle, Christine C. Winterbourn, Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing Blood. ,vol. 92, pp. 3007- 3017 ,(1998) , 10.1182/BLOOD.V92.9.3007.421K47_3007_3017
Steven L. Kunkel, Robert M. Strieter, Mark W. Rolfe, Keita Kasahara, Stephen W. Chensue, Theodore J. Standiford, Ronald M. Allen, Frank S. Becker, Cytokine-induced neutrophil-derived interleukin-8. American Journal of Pathology. ,vol. 141, pp. 397- 407 ,(1992)
Boris Schleiffenbaum, Bernhard Odermatt, Jörg Fehr, Roland Sperb, Inhibition of Leukocyte Emigration Induced During the Systemic Inflammatory Reaction In Vivo Is Not Due to IL-8 Journal of Immunology. ,vol. 161, pp. 3631- 3638 ,(1998)
O Spertini, T J Ernst, J D Griffin, T F Tedder, H B Levine, M P Belvin, Y Kanakura, Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors. Journal of Immunology. ,vol. 145, pp. 576- 584 ,(1990)
Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai, Tsuneyasu Kaisho, Shintaro Sato, Hideki Sanjo, Makoto Matsumoto, Katsuaki Hoshino, Hermann Wagner, Kiyoshi Takeda, Shizuo Akira, A Toll-like receptor recognizes bacterial DNA. Nature. ,vol. 408, pp. 740- 745 ,(2000) , 10.1038/35047123
Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky, Thomas R. Hawn, Eugene C. Yi, David R. Goodlett, Jimmy K. Eng, Shizuo Akira, David M. Underhill, Alan Aderem, The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. ,vol. 410, pp. 1099- 1103 ,(2001) , 10.1038/35074106
Joseph B. Domachowske, Cynthia A. Bonville, Ji-Liang Gao, Philip M. Murphy, Andrew J. Easton, Helene F. Rosenberg, The Chemokine Macrophage-Inflammatory Protein-1α and Its Receptor CCR1 Control Pulmonary Inflammation and Antiviral Host Defense in Paramyxovirus Infection Journal of Immunology. ,vol. 165, pp. 2677- 2682 ,(2000) , 10.4049/JIMMUNOL.165.5.2677
David M. Underhill, Adrian Ozinsky, Adeline M. Hajjar, Anne Stevens, Christopher B. Wilson, Michael Bassetti, Alan Aderem, The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens Nature. ,vol. 401, pp. 811- 815 ,(1999) , 10.1038/44605
Terry K. Means, Fumitaka Hayashi, Kelly D. Smith, Alan Aderem, Andrew D. Luster, The Toll-Like Receptor 5 Stimulus Bacterial Flagellin Induces Maturation and Chemokine Production in Human Dendritic Cells Journal of Immunology. ,vol. 170, pp. 5165- 5175 ,(2003) , 10.4049/JIMMUNOL.170.10.5165
Birgitte Viuff, Kirsten Tjørnehøj, Lars E. Larsen, Christine M. Røntved, Åse Uttenthal, Leif Rønsholt, Soren Alexandersen, Replication and clearance of respiratory syncytial virus: apoptosis is an important pathway of virus clearance after experimental infection with bovine respiratory syncytial virus. American Journal of Pathology. ,vol. 161, pp. 2195- 2207 ,(2002) , 10.1016/S0002-9440(10)64496-3