β-catenin and its multiple partners: promiscuity explained

作者: Lawrence Shapiro

DOI: 10.1038/88532

关键词:

摘要: β-catenin functions both in cadherin-mediated cell adhesion and the Wnt signaling pathway. In these roles, interacts with a multitude of protein partners including cadherins, α-catenin, axin, APC, Tcf family transcription factors. Recent crystal structures show how can achieve this remarkably diverse functionality.

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