Diffuse interstitial pulmonary fibrosis. Pulmonary fibrosis in mice induced by treatment with butylated hydroxytoluene and oxygen

摘要: It is proposed that the pulmonary fibrosis induced in mice by treatment with BHT and oxygen a good experimental model for human fibrosis. The mechanism of synergistic additive effects various agents on injury epithelial mesenchymal interactions occurring during early late phases lung repair could be studied. This used study concentrations diffusely damaged assessment efficacy drugs preventing or resolving excessive collagen accumulation lung. In addition, relationship between emphysema