Effect of air, heliox, and oxygen breathing on air bubbles in aqueous tissues in the rat.

摘要: Our purpose was to examine the behavior of air bubbles in three non-lipid tissues (skeletal muscle, tendon, and anterior chamber eye) during breathing air, helium-oxygen (heliox, 80:20), or oxygen. Air were injected into skeletal muscle tendon rats after decompression from a 1-h exposure at 3.5 atm abs (355 kPa) rat eye without any previous pressure exposure. The studied by photomicroscopy 1 (101 either followed heliox O2 breathing. Muscle: breathing, all initially increased size for period 55-100 min then started shrink. Both shrinking rate as compared air. Bubble decreased more rapidly than Tendon: bubble constant rate; one decrease preceded small increase. During most faster caused short-term increase 4 out 10 bubbles. Otherwise, shrinkage six uninfluenced four O2. Rat eye: shrank observation period. When started, transiently grew 10-35 min, which they began five seven stopped 5-15 both We conclude that will cause aqueous disappear Since promoted gas exchange probably not primarily limited extravascular diffusion these tissues. present experiments suggest may exacerbate limb bends.