Effect of splenectomy on the immune response of the blue gourami Trichogaster trichopterus, to infectious pancreatic necrosis (IPN) virus

摘要: Abstract The effects of splenectomy on the immune response blue gourami, Trichogaster trichopterus , to infectious pancreatic necrosis (IPN) virus was studied. mortality rate recorded in splenectomized fish approximately 50%. Of survivors (9 fish), five had regenerated splenic tissues and four not. Neutralization tests using sera from these indicated that with spleens protected RTG-2 cells against IPN while other group did These findings suggested spleen gourami is major lymphoid organ involved production antibodies. possible site antibodies discussed.