Underutilization of Lynch syndrome screening in a multisite study of patients with colorectal cancer

摘要: The aim of this study was to examine Lynch syndrome screening patients with metastatic colorectal cancer in integrated health-care-delivery organizations. We determined the availability criteria and actual medical records 1,188 diagnosed between 2004 2009 at seven institutions Cancer Research Network. found infrequent use (41/1,188). Family history available for 937 (79%). There sufficient information assess risk using family history–based 719 (77%) documentation. In 391 individuals a syndrome–associated cancer, 107 (27%) could not be evaluated due missing such as age onset. Eleven percent who met Bethesda 25% Amsterdam II were screened syndrome. Recommended guidelines adhered during screening, but no testing method preferred. required decisions is routinely collected seldom used. critical gap collection its guide which may support case implementation universal guidelines. Genet Med 15 12, 933–940.