Omega-3 Polyunsaturated Fatty Acid Supplementation for Reducing Muscle Soreness after Eccentric Exercise: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

摘要: Purpose. This systematic review and meta-analysis was performed to determine the effectiveness of Omega-3 polyunsaturated fatty acid ( PUFA) supplement on muscle soreness after eccentric exercise. Methods. PubMed, EMBASE, CENTRAL, ISI Web Science were searched identify randomized controlled trials (RCTs) that assessed efficacy PUFA Mean difference (MD) associated 95% confidence interval (95% CI) calculated by RevMan 5.3 indicate delayed onset (DOMS) measured two days trainings. Subgroup analyses according duration daily dosage supplements before exercises whether these factors will influence overall effect size. The Grading Recommendations, Assessment, Development, Evaluation (GRADE) approach used evaluate certainty evidence. protocol this registered at PROSPERO CRD42018085869 ). Results. 12 RCTs containing 145 subjects 156 controls included in study. Meta-analysis revealed a significantly decreased DOMS (MD -0.93; CI -1.44, -0.42; ) groups, while no significant differences isometric strength range motion (ROM) detected. However, pooled size for lower than minimal clinically important (MCID) 1.4 10-unit VAS, suggesting less with did not appear be relevant. Conclusion. There is low-quality evidence supplementation does result reduction Isometric improved either (low-quality evidence). To further elucidate role damage area, large-scale are still needed.