Morphological and electrophysiological properties of principal neurons in the rat lateral amygdala in vitro

摘要: In this study, we characterize the electrophysiological and morphological properties of spiny principal neurons in rat lateral amygdala using whole cell recordings acute brain slices. These exhibited a range firing response to prolonged current injection. Responses varied from cells that showed full spike frequency adaptation, spiking three five times, those no adaptation. The differences patterns were largely explained by amplitude afterhyperpolarization (AHP) followed trains. Cells adaptation had large slow AHPs, whereas discharged tonically AHPs much smaller amplitude. During trains, all similar broadening their action potentials. Biocytin-filled pyramidal-like morphologies, differed dendritic complexity, dendrites, degree which they clearly apical versus basal dendrites. Quantitative analysis revealed association between morphology properties. We conclude discharge nucleus, somatic injections, are determined differential distribution ionic conductances rather than through mechanisms rely on morphology.