The amygdala and medial prefrontal cortex: partners in the fear circuit

摘要: Fear conditioning and fear extinction are Pavlovian paradigms extensively used to study the mechanisms that underlie learning memory formation. The neural circuits mediate this evolutionarily conserved, seen in virtually all species from flies humans. In mammals, amygdala medial prefrontal cortex two structures play a key role acquisition, consolidation retrieval of memory, as well fear. These regions have extensive bidirectional connections, recent years, beginning be elucidated. review, we provide an overview our current understanding architecture within cortex. We describe how sensory information is processed these between them thought different aspects learning. Finally, discuss changes may responses following extinction.