摘要: This review summarizes our current knowledge of the regulation cell cycle by cyclin-dependent kinase family (CDK). The CDKs are regulated both binding their cyclin partners, and phosphorylation certain key residues. Cyclin synthesis destruction during cycle, there two broad classes cyclins: START or G1 cyclins, mitotic G2 cyclins. In vivo different cyclins demonstrate a high degree specificity in to each other, it appears that specific cyclin-CDK complexes involved particular events.
参考文章(0)