作者: A. Lee , J. Fox
DOI: 10.1007/978-3-642-75726-6_10
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摘要: Microbiologists interested in the microbial flora of gastrointestinal tract have traditionally ignored stomach. Due to harsh environment resulting from acid secretion, conditions were considered be hostile permanent colonization by bacteria although it was accepted could survive passage into lower bowel. An exception work Savage (1980), who showed gastric mucosa rodents permanently colonized with acid-tolerant lactobacilli and yeasts. However, isolation Helicobacter pylori its association gastroduodenal disease has focussed interest on stomach is now clear that many animal species similar colonizing their surfaces, i.e. humans, dogs, cheetahs, cats, monkeys, ferrets, rats (Lee 1989a). One characteristic ecology environments so called low diversity; is, very numbers are present at any one time (Alexander 1971). This a consequence need for specialized adaptations being required live site. certainly where usually most three bacterial found together. Thus animals inhabiting mucus only present. In humans normally H. pylori. As more isolated other important compare properties order better able identify those factors essential which might involved initiation disease.