Torovirus Pathogenesis and Immune Responses

作者: Armando E. Hoet , Linda J. Saif

DOI: 10.1128/9781555815790.CH23

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摘要: Toroviruses are pleomorphic viruses with a peplomer-bearing envelope containing an elongated tubular nucleocapsid helical symmetry. They contain linear, nonsegmented, positive- and single-stranded polyadenylated RNA genome. Currently only four species recognized as members of the Torovirus genus in Coronaviridae family: equine torovirus (EToV), initially known Berne virus; bovine (BToV), originally Breda human (HToV); porcine torovirus. Torovirus-like (TVL) particles have been detected feces from other animal species, such turkeys, dogs, cats. In addition, antibodies against toroviruses frequently ungulates horses, sheep, goats, pigs. This chapter provides comprehensive review pathogenesis immune responses. A brief epidemiological background highlighting HToVs is also provided.

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