Nitric oxide in paraventricular nuclei of rat hypothalamus under extreme conditions

作者: O. V. Fidelina , O. S. Gorbatyuk , I. G. Akmaev

DOI: 10.1007/BF02496872

关键词:

摘要: The activity of nitroxide synthetase (NOS) was studied histochemically and levels oxytocin vasopressin immunocytochemically in rat hypothalamus paraventricular nuclei on-earth experiments simulating space flight conditions with landing. Colonization NOS found large-cell neurons nuclei. After 15 days under simulated microgravitation followed by 1-day double gravitation a short-term (1 day) macrogravitation, activities content neuropeptides increased experimental animals.

参考文章(11)
Solomon H. Snyder, David S. Bredt, Nitric oxide as a neuronal messenger Trends in Pharmacological Sciences. ,vol. 12, pp. 125- 128 ,(1991) , 10.1016/0165-6147(91)90526-X
L.W. Swanson, P.E. Sawchenko, Paraventricular Nucleus:A Site for the Integration of Neuroendocrine and Autonomic Mechanisms Neuroendocrinology. ,vol. 31, pp. 410- 417 ,(1980) , 10.1159/000123111
John Garthwaite, Sarah L. Charles, Russell Chess-Williams, Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature. ,vol. 336, pp. 385- 388 ,(1988) , 10.1038/336385A0
T. M. Dawson, D. S. Bredt, M. Fotuhi, P. M. Hwang, S. H. Snyder, Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 7797- 7801 ,(1991) , 10.1073/PNAS.88.17.7797
B. T. Hope, G. J. Michael, K. M. Knigge, S. R. Vincent, Neuronal NADPH diaphorase is a nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 2811- 2814 ,(1991) , 10.1073/PNAS.88.7.2811
David S. Bredt, Solomon H. Snyder, Nitric oxide, a novel neuronal messenger. Neuron. ,vol. 8, pp. 3- 11 ,(1992) , 10.1016/0896-6273(92)90104-L