Aggregation of disease-related peptides.
作者： Phuong H. Nguyen , Fabio Sterpone , Philippe Derreumaux
DOI: 10.1016/BS.PMBTS.2019.12.002
关键词:
摘要: Protein misfolding and aggregation of amyloid proteins is the fundamental cause more than 20 diseases. Molecular mechanisms self-assembly formation toxic aggregates are still elusive. Computer simulations have been intensively used to study peptides various amino acid lengths related neurodegenerative We review atomistic coarse-grained short aimed at determining their transient oligomeric structures early late steps.
archives-ouvertes.fr
sci-hub.se 参考文章(122)
Tadashi Ando, Jeffrey Skolnick, On the Importance of Hydrodynamic Interactions in Lipid Membrane Formation Biophysical Journal. ,vol. 104, pp. 96- 105 ,(2013) , 10.1016/J.BPJ.2012.11.3829
Jessica Nasica-Labouze, Phuong H. Nguyen, Fabio Sterpone, Olivia Berthoumieu, Nicolae-Viorel Buchete, Sébastien Coté, Alfonso De Simone, Andrew J. Doig, Peter Faller, Angel Garcia, Alessandro Laio, Mai Suan Li, Simone Melchionna, Normand Mousseau, Yuguang Mu, Anant Paravastu, Samuela Pasquali, David J. Rosenman, Birgit Strodel, Bogdan Tarus, John H. Viles, Tong Zhang, Chunyu Wang, Philippe Derreumaux, Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies Chemical Reviews. ,vol. 115, pp. 3518- 3563 ,(2015) , 10.1021/CR500638N
Andrew J Doig, Philippe Derreumaux, Inhibition of protein aggregation and amyloid formation by small molecules. Current Opinion in Structural Biology. ,vol. 30, pp. 50- 56 ,(2015) , 10.1016/J.SBI.2014.12.004
Sarah A. Petty, Sean M. Decatur, Experimental Evidence for the Reorganization of β-Strands within Aggregates of the Aβ(16−22) Peptide Journal of the American Chemical Society. ,vol. 127, pp. 13488- 13489 ,(2005) , 10.1021/JA054663Y
A.T. Petkova, G. Buntkowsky, F. Dyda, R.D. Leapman, W.-M. Yau, R. Tycko, Solid State NMR Reveals a pH-dependent Antiparallel β-Sheet Registry in Fibrils Formed by a β-Amyloid Peptide Journal of Molecular Biology. ,vol. 335, pp. 247- 260 ,(2004) , 10.1016/J.JMB.2003.10.044
Fahimeh Baftizadeh, Xevi Biarnes, Fabio Pietrucci, Fabio Affinito, Alessandro Laio, Multidimensional view of amyloid fibril nucleation in atomistic detail. Journal of the American Chemical Society. ,vol. 134, pp. 3886- 3894 ,(2012) , 10.1021/JA210826A
Riccardo Pellarin, Amedeo Caflisch, Interpreting the aggregation kinetics of amyloid peptides Journal of Molecular Biology. ,vol. 360, pp. 882- 892 ,(2006) , 10.1016/J.JMB.2006.05.033
Nguyen Truong Co, Mai Suan Li, New method for determining size of critical nucleus of fibril formation of polypeptide chains Journal of Chemical Physics. ,vol. 137, pp. 095101- 095101 ,(2012) , 10.1063/1.4749257
Ana V. Rojas, Adam Liwo, Harold A. Scheraga, A Study of the α-Helical Intermediate Preceding the Aggregation of the Amino-Terminal Fragment of the β Amyloid Peptide (Aβ1–28) Journal of Physical Chemistry B. ,vol. 115, pp. 12978- 12983 ,(2011) , 10.1021/JP2050993
Philippe Derreumaux, Generating ensemble averages for small proteins from extended conformations by Monte Carlo simulations. Physical Review Letters. ,vol. 85, pp. 206- 209 ,(2000) , 10.1103/PHYSREVLETT.85.206