作者: M A Alspaugh , E M Tan
DOI: 10.1172/JCI108007
关键词:
摘要: An extract of human lymphocytes from continous cell culture was used as the antigen source to detect antibodies in sera patients with Sjogren's syndrome (SS). Using double diffusion agarose, 85 per cent a selected group had precepating antibodies. Three precipitating antigen-antibody systems were detected and shown be different those described previously othe systemic rheumatic diseases. The SS temporarily classified precipitins, A, B, C. patinets sicca but without clinical rheumatoid arthritis precipitin A and/or associated system Serum reactants demonstrated by immuno-electrophoresis migrate gamma globulin region. activity serum factors not destroyed treatment 2-mercaptoethanol removed absorption factor sera. reactivity lympuocyte antigens trypsin deoxyribonuclease or ribonuclease.