Plausible Biological Interactions of Low- and Non-Calorie Sweeteners with the Intestinal Microbiota: An Update of Recent Studies.
作者： Julio Plaza-Diaz , Belén Pastor-Villaescusa , Ascensión Rueda-Robles , Francisco Abadia-Molina , Francisco Javier Ruiz-Ojeda
DOI: 10.3390/NU12041153
关键词:
摘要: Sweeteners that are a hundred thousand times sweeter than sucrose are being consumed as sugar substitutes. The effects of sweeteners on gut microbiota composition have not been completely elucidated yet, and numerous gaps related to the effects of nonnutritive sweeteners (NNS) on health still remain. The NNS aspartame and acesulfame-K do not interact with the colonic microbiota, and, as a result, potentially expected shifts in the gut microbiota are relatively limited, although acesulfame-K intake increases Firmicutes and …
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scilit.net参考文章(76)
J. Ballongue, C. Schumann, P. Quignon, Effects of Lactulose and Lactitol on Colonic Microflora and Enzymatic Activity Scandinavian Journal of Gastroenterology. ,vol. 222, pp. 41- 44 ,(1997) , 10.1080/00365521.1997.11720716
Jotham Suez, Tal Korem, Gili Zilberman-Schapira, Eran Segal, Eran Elinav, Non-caloric artificial sweeteners and the microbiome: findings and challenges Gut microbes. ,vol. 6, pp. 149- 155 ,(2015) , 10.1080/19490976.2015.1017700
Gordon B. Robbins, Keith H. Lewis, Fermentation of Sugar Acids by Bacteria Journal of Bacteriology. ,vol. 39, pp. 399- 404 ,(1940) , 10.1128/JB.39.4.399-404.1940
Austin Bradford Hill, THE ENVIRONMENT AND DISEASE: ASSOCIATION OR CAUSATION? Journal of the Royal Society of Medicine. ,vol. 58, pp. 295- 300 ,(1965) , 10.1177/0141076814562718
Cara L. Frankenfeld, Masoumeh Sikaroodi, Evan Lamb, Sarah Shoemaker, Patrick M. Gillevet, High-intensity sweetener consumption and gut microbiome content and predicted gene function in a cross-sectional study of adults in the United States Annals of Epidemiology. ,vol. 25, pp. 736- 742 ,(2015) , 10.1016/J.ANNEPIDEM.2015.06.083
Lewis D. Stegink, Louise C. Wolf-Novak, L. J. Filer, E. F. Bell, E. E. Ziegler, Wilma L. Krause, Marvin C. Brummel, Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria. Journal of Nutrition. ,vol. 117, pp. 1989- 1995 ,(1987) , 10.1093/JN/117.11.1989
Tsuneyuki Oku, Mitsuko Okazaki, Laxative threshold of sugar alcohol erythritol in human subjects Nutrition Research. ,vol. 16, pp. 577- 589 ,(1996) , 10.1016/0271-5317(96)00036-X
Jotham Suez, Tal Korem, David Zeevi, Gili Zilberman-Schapira, Christoph A. Thaiss, Ori Maza, David Israeli, Niv Zmora, Shlomit Gilad, Adina Weinberger, Yael Kuperman, Alon Harmelin, Ilana Kolodkin-Gal, Hagit Shapiro, Zamir Halpern, Eran Segal, Eran Elinav, Artificial sweeteners induce glucose intolerance by altering the gut microbiota Nature. ,vol. 514, pp. 181- 186 ,(2014) , 10.1038/NATURE13793
J.L. Byard, E.W. McChesney, L. Golberg, F. Coulston, Excretion and metabolism of saccharin in man. II. Studies with 14C-labelled and unlabelled saccharin Food and Cosmetics Toxicology. ,vol. 12, pp. 175- 184 ,(1974) , 10.1016/0015-6264(74)90362-9
Claudio Gardana, Paolo Simonetti, Enrica Canzi, Raffaella Zanchi, Piergiorgio Pietta, Metabolism of Stevioside and Rebaudioside A from Stevia rebaudiana Extracts by Human Microflora Journal of Agricultural and Food Chemistry. ,vol. 51, pp. 6618- 6622 ,(2003) , 10.1021/JF0303619