Proximal hypospadias in a male patient with 5?-reductase deficiency: A case reports
作者： Erol Basuguy , Selcuk Otcu
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摘要: Hypospadias is a congenital disorder of male external genital. The newborn showed penoscrotal hypospadias with chordee and microphallus. Endocrine data normal karyotype were suggestive 5? -reductase deficiency. Penoscrotal repair the patient was made .
pediatricurologycasereports.com参考文章(16)
THOMAS O. CARPENTER, JULIANNE IMPERATO-MCGINLEY, SUSAN D. BOULWARE, ROBERT M. WEISS, CEDRIC SHACKLETON, JAMES E. GRIFFIN, JEAN D. WILSON, Variable Expression of 5α-Reductase Deficiency: Presentation with Male Phenotype in a Child of Greek Origin The Journal of Clinical Endocrinology and Metabolism. ,vol. 71, pp. 318- 322 ,(1990) , 10.1210/JCEM-71-2-318
WILLIAM DeFOOR, JEFFREY WACKSMAN, Results of Single Staged Hypospadias Surgery to Repair Penoscrotal Hypospadias With Bifid Scrotum or Penoscrotal Transposition The Journal of Urology. ,vol. 170, pp. 1585- 1588 ,(2003) , 10.1097/01.JU.0000084141.51617.1B
O Hiort, G H Sinnecker, H Willenbring, A Lehners, A Zöllner, D Struve, Nonisotopic single strand conformation analysis of the 5 alpha-reductase type 2 gene for the diagnosis of 5 alpha-reductase deficiency. The Journal of Clinical Endocrinology and Metabolism. ,vol. 81, pp. 3415- 3418 ,(1996) , 10.1210/JCEM.81.9.8784107
Suzan L. Carmichael, Gary M. Shaw, Edward J. Lammer, Environmental and genetic contributors to hypospadias: a review of the epidemiologic evidence. Birth Defects Research Part A-clinical and Molecular Teratology. ,vol. 94, pp. 499- 510 ,(2012) , 10.1002/BDRA.23021
Jeanne M. Manson, Michael C. Carr, Molecular epidemiology of hypospadias: review of genetic and environmental risk factors. Birth Defects Research Part A-clinical and Molecular Teratology. ,vol. 67, pp. 825- 836 ,(2003) , 10.1002/BDRA.10084
Rodolfo Rey, Jean-Yves Picard, Embryology and endocrinology of genital development Baillière's clinical endocrinology and metabolism. ,vol. 12, pp. 17- 33 ,(1998) , 10.1016/S0950-351X(98)80427-8
R.F. Gittes, A.P. McLaughlin, Injection technique to induce penile erection. Urology. ,vol. 4, pp. 473- 474 ,(1974) , 10.1016/0090-4295(74)90025-9
Yanping Wang, Qiang Li, Jiajie Xu, Qingjie Liu, Weiqiu Wang, Yi Lin, Fen Ma, Taiji Chen, Senkai Li, Yan Shen, Mutation analysis of five candidate genes in Chinese patients with hypospadias. European Journal of Human Genetics. ,vol. 12, pp. 706- 712 ,(2004) , 10.1038/SJ.EJHG.5201232
J Imperato-McGinley, Y.-S Zhu, Androgens and male physiology the syndrome of 5α-reductase-2 deficiency Molecular and Cellular Endocrinology. ,vol. 198, pp. 51- 59 ,(2002) , 10.1016/S0303-7207(02)00368-4
Hatem A. Saafan, Two Stages repair of proximal hypospadias: Review of 33 cases Annals of Pediatric Surgery. ,vol. 6, pp. 89- 92 ,(2010)