Host range mutants of human rhinovirus in which nonstructural proteins are altered.

作者: F H Yin , N B Lomax

DOI: 10.1128/JVI.48.2.410-418.1983

关键词:

摘要: Human rhinovirus type 2 did not replicate in nonpermissive mouse cells; the restriction was adsorption but early events of virus replication. Mutants which had been adapted to grow cells following characteristics: (i) no change structural protein, (ii) a larger nonstructural protein and its precursor (iii) an altered viral RNA synthesis. The proteins correlated with host range may be involved

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