NMR backbone resonance assignment of New Delhi metallo-beta-lactamase.
作者： Chendie Yao , Qiong Wu , Guohua Xu , Conggang Li
DOI: 10.1007/S12104-017-9756-5
关键词:
摘要: The emerging of the New Delhi metallo-beta-lactamase (NDM-1) has become one greatest threats to clinical treatment. Although structure NDM-1 been determined by X-ray crystallography, molecular mechanism and process catalysis reaction remain elusive. NMR spectroscopy plays a unique role in characterization conformational dynamics. Here we report backbone 1H, 15N 13C chemical shift assignments heteronuclear multidimensional as well its secondary solution predicted TALOS+.
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