Investigating the position of the hairpin loop in New Delhi metallo-β-lactamase, NDM-1, during catalysis and inhibitor binding

作者: Mahesh Aitha , Abraham J. Moller , Indra D. Sahu , Masaki Horitani , David L. Tierney

DOI: 10.1016/J.JINORGBIO.2015.10.011

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摘要: … This study suggests that the hairpin loop in NDM-1 moves over the metal ion during the catalysis and then moves back to its original position after hydrolysis, which is consistent with a …

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