The inhibitory effect of 3,3',4,5'-tetrahydroxystilbene, a constituent of Cassia garrettiana, on anti-IgE-induced histamine release from human basophils in vitro.

作者: Yoshihiko INAMORI , Masafumi OGAWA , Hiroshi TSUJIBO , Kimiye BABA , Mitsugi KOZAWA

DOI: 10.1248/CPB.39.805

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摘要: 3,3',4,5'-Tetrahydroxystilbene (I), a constituent of Cassia garrettiana, strongly inhibited the anti-IgE-induced histamine release from human basophils in vitro at concentrations 3 to 30 microM. Considering that disodium cromoglycate showed no significant inhibitory activity this assay method, strong effect I should be emphasized.

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