Impact of Metabolic Syndrome on Fibrosis Progression in Chronic Viral Hepatitis B Infection
作者： Cem Aygun
DOI: 10.4172/2167-0943.1000175
关键词:
摘要: Many factors may increase the risk of fibrosis development in chronic viral hepatitis infections. As burden obesity and metabolic syndrome has been increasing recent years, there is growing concern regarding association between cases. However data influence on progression B virus (HBV) infection limited. Metabolic a constellation problems that includes insulin resistance, obesity, hypertension, hyperlipidemia. Initially, epidemiologic demonstrated HBsAg-positive serostatus was positively correlated with high syndrome; later on, HBV considered as “metabolovirus” because gene expression key genes hepatocytes found to be similarly regulated. not only accelerate liver disease patients but also induce cirrhosis or even hepatocellular carcinoma development. This review article it aimed highlight infection.
omicsgroup.org参考文章(33)
Tsun-Jen Cheng, Ta-Chen Su, Yuan-Teh Lee, Hsu-Ping Chien, Jung-Der Wang, Chronic Hepatitis B Virus Infection and Dyslipidemia Journal of the Formosan Medical Association. ,vol. 103, pp. 286- 291 ,(2004) , 10.29828/JFMA.200404.0006
Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky, Marc Montminy, PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 Nature Medicine. ,vol. 10, pp. 530- 534 ,(2004) , 10.1038/NM1044
VALERIO GRISTINA, MARIA GRAZIA CUPRI, MARTINA TORCHIO, CLAUDIO MEZZOGORI, LAURA CACCIABUE, MARCO DANOVA, Diabetes and cancer: A critical appraisal of the pathogenetic and therapeutic links. Biomedical Reports. ,vol. 3, pp. 131- 136 ,(2015) , 10.3892/BR.2014.399
Paresh Dandona, Ahmad Aljada, Ajay Chaudhuri, Priya Mohanty, Rajesh Garg, Metabolic Syndrome A Comprehensive Perspective Based on Interactions Between Obesity, Diabetes, and Inflammation Circulation. ,vol. 111, pp. 1448- 1454 ,(2005) , 10.1161/01.CIR.0000158483.13093.9D
Jee-Fu Huang, Wan-Long Chuang, Ming-Lung Yu, Sung-Hua Yu, Chung-Feng Huang, Ching-I Huang, Ming-Lun Yeh, Meng-Hsuan Hsieh, Jeng-Fu Yang, Zu-Yau Lin, Shinn-Chern Chen, Chia-Yen Dai, Wen-Yu Chang, Hepatitis C virus infection and metabolic syndrome---a community-based study in an endemic area of Taiwan. Kaohsiung Journal of Medical Sciences. ,vol. 25, pp. 299- 305 ,(2009) , 10.1016/S1607-551X(09)70520-0
Sheng-Han Wang, Shiou-Hwei Yeh, Wei-Hsiang Lin, Hurng-Yi Wang, Ding-Shinn Chen, Pei-Jer Chen, Identification of androgen response elements in the enhancer I of hepatitis B virus: a mechanism for sex disparity in chronic hepatitis B. Hepatology. ,vol. 50, pp. 1392- 1402 ,(2009) , 10.1002/HEP.23163
Amir Shlomai, Yosef Shaul, The metabolic activator FOXO1 binds hepatitis B virus DNA and activates its transcription. Biochemical and Biophysical Research Communications. ,vol. 381, pp. 544- 548 ,(2009) , 10.1016/J.BBRC.2009.02.078
Harry Yoon, Jeong Guil Lee, Jeong Hwan Yoo, Myung Su Son, Dae Young Kim, Seong Gyu Hwang, Kyu Sung Rim, Effects of Metabolic Syndrome on Fibrosis in Chronic Viral Hepatitis Gut and Liver. ,vol. 7, pp. 469- 474 ,(2013) , 10.5009/GNL.2013.7.4.469
Grace Lai–Hung Wong, Henry Lik–Yuen Chan, Hoi–Yun Chan, Pete Chi–Hang Tse, Yee–Kit Tse, Christy Wing–Hin Mak, Stanley King–Yeung Lee, Zoe Man–Yi Ip, Andrew Ting–Ho Lam, Henry Wing–Hang Iu, Joyce May–Sum Leung, Vincent Wai–Sun Wong, Accuracy of risk scores for patients with chronic hepatitis B receiving entecavir treatment. Gastroenterology. ,vol. 144, pp. 933- 944 ,(2013) , 10.1053/J.GASTRO.2013.02.002
Chi–Ling Chen, Hwai–I. Yang, Wei–Shiung Yang, Chun–Jen Liu, Pei–Jer Chen, San–Lin You, Li–Yu Wang, Chien–An Sun, Sheng–Nan Lu, Ding–Shin Chen, Chien–Jen Chen, Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan. Gastroenterology. ,vol. 135, pp. 111- 121 ,(2008) , 10.1053/J.GASTRO.2008.03.073