Developing the Scope of O→C Aryl Migrations: Exploring Amide Substrates as Potential Precursors for Asymmetric Reactions
作者： Dana Ameen , Timothy J. Snape
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摘要: A new and mild method for the production of diasteromerically enriched α-aryl carbonyl compounds has been achieved. Although only modest diastereoselectivies are observed, they demonstrate potential further optimisation. It also appears that reactions proceed through a five-membered spirocyclic transition state rearrange, whereas those proceeding six-membered do not, but stop at diaryl ether stage.
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sci-hub.se 参考文章(23)
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