Compositions and methods for treating substance abuse disorders

作者: Carol Gloff , Julie Straub , Michael Detke

DOI:

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摘要: The present invention is directed to compositions and methods for treating substance abuse disorders addiction. In particular, this combinations of low doses a cortisol synthesis inhibitor, such as metyrapone, in combination with benzodiazepine, oxazepam. the include pharmaceutical that are safe efficacious animals humans.

参考文章(7)
Clark Allphin, Andrea Rourke, Maura Murphy, Immediate release dosage forms of sodium oxybate ,(2009)
Anita S Kablinger, Marie A Lindner, Stephanie Casso, Franz Hefti, George DeMuth, Barbara S Fox, Lindsay A McNair, Bruce G McCarthy, Nicholas E Goeders, Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study. Journal of Psychopharmacology. ,vol. 26, pp. 973- 981 ,(2012) , 10.1177/0269881111430745
N GOEDERS, G GUERIN, Effects of the Combination of Metyrapone and Oxazepam on Cocaine and Food Self-administration in Rats Pharmacology, Biochemistry and Behavior. ,vol. 91, pp. 181- 189 ,(2008) , 10.1016/J.PBB.2008.07.005
Nicholas E. Goeders, Glenn F. Guerin, Christopher D. Schmoutz, The Combination of Metyrapone and Oxazepam for the Treatment of Cocaine and Other Drug Addictions Advances in pharmacology (San Diego). ,vol. 69, pp. 419- 479 ,(2014) , 10.1016/B978-0-12-420118-7.00011-1