Bandas oligoclonales en líquido cefalorraquídeo de pacientes con esclerosis múltiple del Hospital Militar Central, Bogotá DC.

作者: Sergio Cabrera-Limpias , Juan Carlos González , Consuelo Romero-Sánchez , Gabriel Centanaro , Jean Paul Vergara

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摘要: INTRODUCTION: multiple sclerosis is the most common disabling neurological disease in youth adults. So far there no accurate test for diagnosis. The laboratory tests have become very important because include assessment of intrathecal antibody production diagnosis this disease. OBJETIVE: describe behavior cerebrospinal fluid oligoclonal bands a group patients MATERIAL AND METHODS: descriptive case series, with population MS currently receiving specific treatment Hospital Militar Central Bogota. absolute frequencies and measures central tendency variables studied were calculated. RESULTS: among described are 26 MS, mean age 43 years old (SD +/- 8.542). 75.1% (19) females 26.9% (7) male. 50% (13) had positive bands.. CONCLUSION: standardized technique determining fluid, as high-resolution agarose gel electrophoresis authors obtained similar results reported international literature. It should make all efforts to introduce detection BO internationally recommended named "isoelectric focusing", who simultaneously compared serum that can get great sensitivity high negative predictive value.

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