Across Culture and Health Systems: America

摘要: Recognition of families with high penetrance young-onset colorectal cancer has existed for over a century [1, 2, 3]. However, concerted efforts to define these high-penetrance diseases occurred much later [4, 5]. Once the molecular basis hereditary syndromes was elucidated, clinical and research toward identification, care, management individuals at risk experienced an exponential growth within last two decades.