Age as a limiting factor for successful sperm retrieval in patients with nonmosaic Klinefelter's syndrome.

作者: Hiroshi Okada , Kazumasa Goda , Yasuhisa Yamamoto , Nikolaos Sofikitis , Ikuo Miyagawa

DOI: 10.1016/J.FERTNSTERT.2005.05.053

关键词:

摘要: Objective To determine factors affecting successful sperm retrieval by testicular extraction in patients with nonmosaic Klinefelter's syndrome. Design Medical record analysis for syndrome who underwent extraction. Setting Three university-based tertiary centers. Patient(s) Fifty-one nonobstructive azoospermia related to Intervention(s) Testicular Main Outcome Measure(s) Correlation of patient characteristics; serum concentrations luteinizing hormone (LH), follicle-stimulating (FSH), and testosterone (T); as well volume success Result(s) We succeeded obtaining spermatozoa 26 failed 25. Levels LH, FSH, T did not differ between groups defined failure. Median ages were 31 38 years, respectively (statistically significant difference). When we analyzed rates two ( Conclusion(s) should be recommended before the critical age 35 years.

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