A Comparison by Means of the Complement-Fixation Test of the Relative Potencies of Chloramphenicol, Aureomycin, and Terramycin in Experimental Q Fever Infections in Embryonated Eggs

摘要: In the course of screening a series compounds for anti-rickettsial activity, procedure was investigated which takes advantage complement-fixation test as means estimating rickettsial growth in chick embryos. The activity has previously been assessed infected embryos either by measuring increase prolongation life or determining infectiousness yolk sacs treated at various times after treatment combination these two methods (1–6). effectiveness also estimated terms numbers organisms observed stained smears made from tissues (7, 8). These have their limitations and defects. A antibiotic should measure, directly possible, effect substance on present any time following treatment, compared with untreated controls.