Perfil do uso de drogas modificadoras de doença no Registro Brasileiro de Espondiloartrites

摘要: Introduction: Few studies have evaluated the profile of use disease modifying drugs (DMD) in Brazilian patients with spondyloarthritis (SpA). Methods: A common research protocol was applied prospectively 1505 classified as SpA by criteria European Spondyloarthropathies Study Group (ESSG), followed at 29 referral centers Rheumatology Brazil. Demographic and clinical variables were obtained evaluated, analyzing their correlation DMDs methotrexate (MTX) sulfasalazine (SSZ). Results: At least one DMD used 73.6 % patients: MTX 29.2 SSZ 21.7%, while 22.7 both drugs. The significantly associated peripheral involvement, axial two more administered, separately or combination, mixed involvement (p < 0.001). a Caucasian ethnicity (MTX , p = 0.014), inflammatory back pain (SSZ, 0.002) buttock 0.030), neck (MTX, 0.042), arthritis lower limbs 0.001), upper enthesitis 0.007), dactylitis bowel 0.001) nail Conclusion: reported than 70% large cohort SpA, involvement.