Recent Developments of Flexible and Stretchable Electrochemical Biosensors.

作者: Xudong Yang , Huanyu Cheng

DOI: 10.3390/MI11030243

关键词:

摘要: The skyrocketing popularity of health monitoring has spurred increasing interest in wearable electrochemical biosensors. Compared with the traditionally rigid and bulky biosensors, flexible stretchable devices render a unique capability to conform complex, hierarchically textured surfaces human body. With recognition element (e.g., enzymes, antibodies, nucleic acids, ions) selectively react target analyte, biosensors can convert types concentrations chemical changes body into electrical signals for easy readout. Initial exploration integrates electrodes on textile thin-film substrate materials. A property is needed device form an intimate contact skin surface deform various natural motions. Thus, materials structures have been exploited ensure effective function biosensor. In this mini-review, we summarize recent development including their principles, representative application scenarios saliva, tear, sweat, interstitial fluid), structures. While great strides made challenges still exist, which represents small fraction opportunities future burgeoning field.

参考文章(205)
Tsuyoshi Minami, Tsubasa Sato, Tsukuru Minamiki, Kenjiro Fukuda, Daisuke Kumaki, Shizuo Tokito, A novel OFET-based biosensor for the selective and sensitive detection of lactate levels Biosensors and Bioelectronics. ,vol. 74, pp. 45- 48 ,(2015) , 10.1016/J.BIOS.2015.06.002
Jayoung Kim, Somayeh Imani, William R de Araujo, Julian Warchall, Gabriela Valdés-Ramírez, Thiago RLC Paixão, Patrick P Mercier, Joseph Wang, None, Wearable salivary uric acid mouthguard biosensor with integrated wireless electronics Biosensors and Bioelectronics. ,vol. 74, pp. 1061- 1068 ,(2015) , 10.1016/J.BIOS.2015.07.039
Ji Hyun Ryu, Seonki Hong, Haeshin Lee, Bio-inspired adhesive catechol-conjugated chitosan for biomedical applications: A mini review Acta Biomaterialia. ,vol. 27, pp. 101- 115 ,(2015) , 10.1016/J.ACTBIO.2015.08.043
G. Rao, R. H. Guy, P. Glikfeld, W. R. LaCourse, L. Leung, J. Tamada, R. O. Potts, N. Azimi, Reverse iontophoresis: noninvasive glucose monitoring in vivo in humans. Pharmaceutical Research. ,vol. 12, pp. 1869- 1873 ,(1995) , 10.1023/A:1016271301814
N Fogh-Andersen, B M Altura, B T Altura, O Siggaard-Andersen, Composition of interstitial fluid. Clinical Chemistry. ,vol. 41, pp. 1522- 1525 ,(1995) , 10.1093/CLINCHEM/41.10.1522
Andreas Weltin, Jochen Kieninger, Barbara Enderle, Anne-Kathrin Gellner, Brita Fritsch, Gerald A Urban, None, Polymer-based, flexible glutamate and lactate microsensors for in vivo applications. Biosensors and Bioelectronics. ,vol. 61, pp. 192- 199 ,(2014) , 10.1016/J.BIOS.2014.05.014
Haixia Yu, Dachao Li, Robert C. Roberts, Kexin Xu, Norman C. Tien, An Interstitial Fluid Transdermal Extraction System for Continuous Glucose Monitoring IEEE\/ASME Journal of Microelectromechanical Systems. ,vol. 21, pp. 917- 925 ,(2012) , 10.1109/JMEMS.2012.2192910
Seung-Kyun Kang, Suk-Won Hwang, Huanyu Cheng, Sooyoun Yu, Bong Hoon Kim, Jae-Hwan Kim, Yonggang Huang, John A. Rogers, Dissolution Behaviors and Applications of Silicon Oxides and Nitrides in Transient Electronics Advanced Functional Materials. ,vol. 24, pp. 4427- 4434 ,(2014) , 10.1002/ADFM.201304293
Joshua Ray Windmiller, Amay Jairaj Bandodkar, Gabriela Valdés-Ramírez, Serguey Parkhomovsky, Alexandra Gabrielle Martinez, Joseph Wang, Electrochemical sensing based on printable temporary transfer tattoos Chemical Communications. ,vol. 48, pp. 6794- 6796 ,(2012) , 10.1039/C2CC32839A