Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system.
作者： A. Endimiani , J. M. DePasquale , S. Forero , F. Perez , A. M. Hujer
DOI: 10.1093/JAC/DKP327
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摘要: Results: Seven KPC-Kp strains were isolated from different patients located at a single LTACH, with further three isolates being recovered hospitals. All in the LTACH and one hospital patient genetically related shared PFGE patterns that clustered known sequence type (ST) 258 strains. These highly resistant to carbapenems (MICs� 32 mg/L) due an increased level of KPC expression loss Omps. Rectal colonization was documented all isolates. Treatment failures common (crude mortality rate 69%). Active surveillance enhanced infection control practices terminated outbreak. Conclusions: The detection represents serious therapeutic challenge new clinical setting. speed which epidemic is spreading our healthcare system mandates urgent action.
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