Serum thrombopoietin and plasma glycocalicin concentrations as useful diagnostic markers in thrombocytopenic disorders.
作者： S. Kunishima , T. Tahara , T. Kato , S. Kobayashi , H. Saito
DOI: 10.1111/J.1600-0609.1996.TB00492.X
关键词:
摘要: Using enzyme-linked immunosorbent assays, we measured the concentrations of serum thrombopoietin (TPO) and plasma glycocalicin, a proteolytic fragment platelet glycoprotien Ib alpha, in 13 patients with myelodysplastic syndrome (MDS), aplastic anaemia (AA) or idiopathic thrombocytopenic purpura (ITP). In AA MDS, TPO were remarkably increased, their glycocalicin decreased compared normal control individuals. ITP, however, levels not changed as much AA/MDS spite same degree thrombocytopenia. During immunosuppressive treatment ITP patients, there was an inverse relationship between level count. Thus, measurements are useful for diagnosis thrombocytopenia, our results from did support model which suggested simple feedback regulation
elsevier.com
sci-hub.se 参考文章(12)
ShinjI Kunishima, Klyotaka Hayashi, Sentaro Kobayashi, Tomokl Naoe, Ryuzo Ohno, New enzyme-linked immunosorbent assay for glycocalicin in plasma. Clinical Chemistry. ,vol. 37, pp. 169- 172 ,(1991) , 10.1093/CLINCHEM/37.2.169
Si Lok, Kenneth Kaushansky, Richard D. Holly, Joseph L. Kuijper, Catherine E. Lofton-Day, Pieter J. Oort, Francis J. Grant, Mark D. Heipel, Steve K. Burkhead, Janet M. Kramer, L. Anne Bell, Cindy A. Sprecher, Hal Blumberg, Rebecca Johnson, Donna Prunkard, Andrew F. T. Ching, Shannon L. Mathewes, Mason C. Bailey, John W. Forstrom, Michele M. Buddle, Sherri G. Osborn, Simon J. Evans, Paul O. Sheppard, Scott R. Presnell, Patrick J. O'Hara, Fredrick S. Hagen, Gerald J. Roth, Donald C. Foster, Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo Nature. ,vol. 369, pp. 565- 568 ,(1994) , 10.1038/369565A0
P J Ballem, G M Segal, J R Stratton, T Gernsheimer, J W Adamson, S J Slichter, Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance. Journal of Clinical Investigation. ,vol. 80, pp. 33- 40 ,(1987) , 10.1172/JCI113060
Frederic J. de Sauvage, Philip E. Hass, Susan D. Spencer, Beth E. Malloy, Austin L. Gurney, Steven A. Spencer, Walter C. Darbonne, William J. Henzel, Suzy C. Wong, Wun-Jing Kuang, Karl J. Oles, Bruce Hultgren, Lawrence A. Solberg, David V. Goeddel, Dan L. Eaton, Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand Nature. ,vol. 369, pp. 533- 538 ,(1994) , 10.1038/369533A0
John Kelton, Steven Gibbons, Autoimmune platelet destruction: idiopathic thrombocytopenic purpura. Seminars in Thrombosis and Hemostasis. ,vol. 8, pp. 83- 104 ,(1982) , 10.1055/S-2007-1005045
Kenneth Kaushansky, Si Lok, Richard D. Holly, Virginia C. Broudy, Nancy Lin, Mason C. Bailey, John W. Forstrom, Michele M. Buddle, Pieter J. Oort, Fredrick S. Hagen, Gerald J. Roth, Thalia Papayannopoulou, Donald C. Foster, Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature. ,vol. 369, pp. 568- 571 ,(1994) , 10.1038/369568A0
Yoshiaki Sohma, Hiromichi Akahori, Naohiko Seki, Tada-aki Hori, Kinya Ogami, Takashi Kato, Yoshihiro Shimada, Kazuo Kawamura, Hiroshi Miyazaki, Molecular cloning and chromosomal localization of the human thrombopoietin gene FEBS Letters. ,vol. 353, pp. 57- 61 ,(1994) , 10.1016/0014-5793(94)01008-0
Françoise Wendling, Eugene Maraskovsky, Najet Debili, Christina Florindo, Mark Teepe, Monique Titeux, Nassia Methia, Janine Breton-Gorius, David Cosman, William Vainchenker, c-Mpl ligand is a humoral regulator of megakaryocytopoiesis Nature. ,vol. 369, pp. 571- 574 ,(1994) , 10.1038/369571A0
TD Bartley, J Bogenberger, P Hunt, Y-S Li, HS Lu, F Martin, M-S Chang, B Samal, JL Nichol, S Swift, MJ Johnson, R-Y Hsu, VP Parker, S Suggs, JD Skrine, LA Merewether, C Clogston, E Hsu, MM Hokom, A Hornkohl, E Choi, M Pangelinan, Y Sun, V Mar, J McNinch, L Simonet, F Jacobsen, C Xie, J Shutter, H Chute, R Basu, L Selander, D Trollinger, L Sieu, D Padilla, G Trail, G Elliott, R Izumi, Tl Covey, J Crouse, A Garcia, W Xu, J Del Castillo, J Biron, S Cole, MC-T Hu, R Pacifici, I Ponting, C Saris, D Wen, YP Yung, H Lin, RA Rosselman, Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI Cell. ,vol. 77, pp. 1117- 1124 ,(1994) , 10.1016/0092-8674(94)90450-2
Shinji Kunishima, Sentaro Kobayashi, Tomoki Naoe, Increased but highly dispersed levels of plasma glycocalicin in patients with disseminated intravascular coagulation. European Journal of Haematology. ,vol. 56, pp. 173- 177 ,(2009) , 10.1111/J.1600-0609.1996.TB01338.X