Use of normalized total dose to represent the biological effect of fractionated radiotherapy.

摘要: There are currently a number of radiobiological models to account for the effects dose fractionation and time. Normalized total (NTD) is not another new model but previously reported, clinically useful form in which represent biological effect, determined by any specific dose-fractionation model, course radiation using single set standardized, easily understood terminology. The generalized NTD reviewed this paper describes effect radiotherapy administered with nonstandard as Gy that could be given reference such 2 per fraction, 5 fractions week would produce an equivalent (probability complications or tumor control) predicted formula. use normalized several different exponential linear-quadratic dose-fraction formulas presented.