Cochlear pathology following chronic electrical stimulation using non charge balanced stimuli.

摘要: During the course of a chronic intracochlear electrical stimulation study using charge balanced biphasic current pulses, one animal inadvertently received short period direct (DC) at level approximately 1 μA. Subsequent, was chronically stimulated poorly waveform that produced DC 2 Extensive pathological changes were observed within cochlea. These included widespread spiral ganglion cell loss and new bone growth extended throughout all turns Significant in morphology electrically evoked auditory brainstem response (EABR) associated with these changes. EABRs recorded prior to exhibited normal morphology. However, responses during dominated by latency believed be vestibular origin. thresholds also significantly higher than levels ...