Dobutamine stress magnetocardiography for the detection of significant coronary artery stenoses - a prospective study in comparison with simultaneous 12-lead electrocardiography.

摘要: BACKGROUND Exercise electrocardiography is an imperfect test for the detection of coronary artery disease (CAD). Magnetocardiography detects cardiac electrical disturbances associated with myocardial ischemia. We prospectively investigated accuracy high-dose dobutamine stress magnetocardiography (DS-MCG) and simultaneous (DS-ECG) significant CAD. METHODS 100 patients intermediate pre-test probability CAD underwent DS-MCG using a multichannel magnetometer prior to invasive angiography. Patients were examined at rest during standard dobutamine-atropine scheme. Significant reduction epicardial current strength/density stress, reconstructed from magnetic field map superposed on virtual heart model indicates A 12-lead DS-ECG was recorded simultaneously. stenosis defined as > or = 70% lumen reduction. RESULTS Without beta-blocker all reached targeted rate. The image quality sufficient analysis in patients. In 19 ruled out angiographically. Thirty two seven revealed stenoses 30-49% 50-69%, respectively. 42 we found 70%. 41 these sensitivity 97.6% 26.2%, specificity 82.8% 82.8%, CONCLUSIONS can be performed dobutamine/atropine protocol. yields significantly higher than DS-ECG.