Biomarker-guided management of acute kidney injury.
作者： Sandra L. Kane-Gill , Melanie Meersch , Max Bell
DOI: 10.1097/MCC.0000000000000777
关键词:
摘要: PURPOSE OF REVIEW The current narrative review discusses practical applications of stress and damage biomarkers for the management acute kidney injury (AKI) based on clinical trials real-world evaluations. RECENT FINDINGS In 2013 with discovery validation study AKI (Sapphire) advancement in care was provided allowing early identification patients at high risk developing AKI. It combination new Kidney Disease Improving Global Outcomes (KDIGO) guidelines managing that an opportunity to improve patient care. 2017, PrevAKI implemented KDIGO guideline high-risk identified by followed 2018 BigPAK used a similar approach, both which demonstrated positive outcomes Next, evaluations supporting biomarker guided practice. Also, proposals better nephrotoxin management, major modifiable exposure prevent AKI, were foresight identifying patients. SUMMARY Stress biomarker-based approaches seem be promising thus offers ameliorate drug-associated
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