NOVEL SESQUITERPENOID STAT3 INHIBITORS
作者： Ui Joung Youn , Dianqing Sun , Spuakit Wongwiwatthananukit , James Turkson , Leng Chee Chang
DOI:
关键词:
摘要: The present disclosure provides a method of purifying pharmaceutical compositions consisting essentially STAT3 inhibitors from mixture compounds, comprising used to inhibit in tumor cells, and certain pharmaceutically acceptable salts thereof, methods use. features, some embodiments, novel, potent selective inhibitors, including sesquiterpene lactone inhibitors.
lens.org参考文章(4)
Poyil Pratheeshkumar, Girija Kuttan, Modulation of cytotoxic T lymphocyte, natural killer cell, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by Vernonia cinerea L. and vernolide-A in BALB/c mice via enhanced production of cytokines IL-2 and IFN-γ. Immunopharmacology and Immunotoxicology. ,vol. 34, pp. 46- 55 ,(2012) , 10.3109/08923973.2011.574703
Yu-Liang Yang, Sue-Ming Chang, Ching-Chung Wu, Pei-Wen Hsieh, Shu-Li Chen, Fang-Rong Chang, Wen-Chun Hung, Hamad H. Issa, Yang-Chang Wu, Cytotoxic sesquiterpene lactones from Pseudoelephantopus spicatus. Journal of Natural Products. ,vol. 70, pp. 1761- 1765 ,(2007) , 10.1021/NP070331Q
R. Romanezi da Silveira, M.A. Foglio, J.A.R. Gontijo, Effect of the crude extract of Vernonia polyanthes Less. on blood pressure and renal sodium excretion in unanesthetized rats. Phytomedicine. ,vol. 10, pp. 127- 131 ,(2003) , 10.1078/094471103321659825
John Meyer, Control apparatus for tractors ,(1921)